Wirkt Psilocybin nachhaltig antidepressiv?” (Does Psilocybin Have a Lasting Antidepressant Effect?)
The paper "Wirkt Psilocybin nachhaltig antidepressiv?" explores the long-term antidepressant effects of psilocybin through a systematic review and meta-analysis of 12 studies, finding significant improvements in depressive symptoms in both short-term and medium-term follow-ups. While the long-term effects remain inconclusive due to limited data, psilocybin was generally well-tolerated with mild to moderate transient adverse events. The authors emphasize the need for further research to establish long-term effects, standardized dosing regimens, and to continue investigating the safety and efficacy of psilocybin as a potential treatment for depression.